Nemesis spawns: These rare, high level atherials and aether corruptions won't spawn until you hit the lowest reputation with those factions, which won't happen until much later on a 2nd - 3rd playthrough on a higher difficulty.Bosses: Such as Commander Lucius, Warden Krieg, Herald Of The Flame, or The Amalgamation.Heroic creatures: These aetherials and aether corruptions are marked with the star next to their name and typically have extra titles such as Azar The Wrathful, Aetheron The Plaguebearer, or Kamladris the Rimeheart.Tainted Brain Matter will drop randomly from these creature types: Instead on relying on chests to effectively farm Tainted Brain Matter, your best bet is to go anywhere where aetherials and aether corruption creatures spawn at a high level.
The locked chests that have to be opened with dynamite in Deadman's Gulch also occasionally drop them.įrankly, the percentage chance on chests is low enough that its more of a "Hey, cool, it finally dropped," than anything that can be reliably farmed, however, so this isn't the best way to go about finding rare crafting ingredients. In particular, I've had success finding Tainted Brain Matter after defeating The Master Of Flesh and opening the chests labeled as The Master's Trove at the end of Ashes of Malmouth.
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